Maître de Conférence des Universitaires – Praticien Hospitalier
Service de Pathologie Est, Hôpital Neurologique
Diplômes
- Doctorat d’Etat en Médecine (1975), Faculté de Médecine de Lyon
- Certificat d’Etudes Spéciales d’Anatomie Pathologique (1976), Faculté de Médecine de Lyon
- Doctorat d’Etat de Biologie Humaine, Section Anatomie Pathologique Mention Neuropathologie (1989), Faculté de Médecine Aix Marseille
- Certificat d’Etudes Supérieures d’Anatomie Pathologique des Animaux de Laboratoire (1986-1988), Ecole Nationale Vétérinaire de Toulouse
Fonction Hospitalière
- Maître de Conférences des Universités - Praticien Hospitalier, Hôpital Neurologique de Lyon
Activités d’enseignements
2ème cycle :
- Enseignement dirigé d’Anatomie Pathologique, UER Alexis Carrel
- Cours aux étudiants en médecine de l’Hôpital Neurologique :
. Enseignement théorique, cours hebdomadaires
. Enseignement pratique de Neuropathologie aux étudiants hospitaliers du Service de Neuropathologie
- Cours magistraux d’Anatomie Pathologique DCEM 1
3ème cycle :
- Participation à l’enseignement des DES-DIS de Neurochirurgie
- Participation à l’enseignement du DES/DIS d’Anatomie et Cytologie Pathologiques
- Participation à l’enseignement de la maîtrise de Biologie Humaine : « Méthodologie en Anatomie Pathologique »
- Participation à l’enseignement de l’attestation universitaire de Cytopathologie (Pr F. THIVOLET-BEJUI)
- Participation à l’enseignement de l’AEU de Thanatologie et Criminalistique (Médecine Légale) (Pr MALICIER)
- Participation à l’enseignement de l’EPU de Neuropathologie (Pr HASSOUN), Tumeurs de la région pinéale
- Participation à l’enseignement de DESC de Neuropathologie
- Participation au DIU de Neuro-Oncologie
Responsabilités administratives
- Référent pour les tumeurs de la région pinéale depuis 1994
- Responsable du secteur tumeur de la banque Neurobiotec
- Référent et coordinatrice du groupe de relecture des tumeurs pédiatriques du système nerveux central pour la SFCE
- Membre du CSS8 neurosciences INSERM de 2003 à 2007
- Coordinatrice pour la région Rhône Alpes du DESC de Neuropathologie depuis 2004
- Expert pour l’Agence Nationale de la Recherche (ANR) : 2006
Publications
2000
Fauchon F, Jouvet A, Paquis P, Saint-Pierre G, Mottolese C, Ben Hassel M, Chauveinc L, Sichez JP, Philippon J, Schlienger M, Bouffet E. Parenchymal pineal tumors: a clinicopathological study of 76 cases. Int J Radiat Oncol Biol Phys, 2000, 46:959-68.
Jouvet A, Saint-Pierre G, Fauchon F, Privat K, Bouffet E, Ruchoux MM, Chauveinc L, Fevre-Montange M. Pineal parenchymal tumors: a correlation of histological features with prognosis in 66 cases. Brain Pathol, 2000, 10:49-60.
2001
Bret P, Jouvet A, Madarassy G, Guyotat J, Trouillas J. Visceral cancer metastasis to pituitary adenoma: report of two cases. Surg Neurol, 2001, 55:284-90.
Frappaz D, Jouvet A, Pierre GS, Giammarile F, Guyotat J, Deruty R, Jouanneau E, Ranchere-Vince D. Lack of evidence of osteo-medullary metastases at diagnosis in patients with high grade gliomas.J Neurooncol, 2001, 52:249-52.
Guyotat J, Champier J, Jouvet A, Signorelli F, Houzard C, Bret P, Saint Pierre G, Fevre Montange M. Differential expression of somatostatin receptors in ependymoma: implications for diagnosis. Int J Cancer, 2001, 95:144-51.
Guyotat J, Champier J, Pierre GS, Jouvet A, Bret P, Brisson C, Belin MF, Signorelli F, Fèvre-Montange M. Differential expression of somatostatin receptors in medulloblastoma. J Neurooncol, 2001, 51:93-103.
Masuoka J, Brandner S, Paulus W, Soffer D, Vital A, Chimelli L, Jouvet A, Yonekawa Y, Kleihues P, Ohgaki H. Germline SDHD mutation in paraganglioma of the spinal cord. Oncogene, 2001, 20:5084-6.
Mottolese C, Hermier M, Stan H, Jouvet A, Saint-Pierre G, Froment JC, Bret P, Lapras C. Central nervous system cavernomas in the pediatric age group. Neurosurg Rev, 2001, 24:55-71.
2002
Brisson C, Lelong-Rebel I, Mottolese C, Jouvet A, Fèvre-Montange M, Saint Pierre G, Rebel G, Belin MF. Establishment of human tumoral ependymal cell lines and coculture with tubular-like human endothelial cells. Int J Oncol, 2002, 21:775-85.
Ferreri AJ, Reni M, Pasini F, Calderoni A, Tirelli U, Pivnik A, Aondio GM, Ferrarese F, Gomez H, Ponzoni M, Borisch B, Berger F, Chassagne C, Iuzzolino P, Carbone A, Weis J, Pedrinis E, Motta T, Jouvet A, Barbui T, Cavalli F, Blay JY. A multicenter study of treatment of primary CNS lymphoma. Neurology, 2002, 58:1513-20.
Guyotat J, Signorelli F, Desme S, Frappaz D, Madarassy G, Fèvre-Montange M, Jouvet A, Bret P. Intracranial ependymomas in adult patients: analyses of prognostic factors. J Neurooncol, 2002, 60:255-68.
Hermier M, Cotton F, Saint-Pierre G, Jouvet A, Ongolo-Zogo P, Fischer G, Froment JC. Myelopathy and sciatica induced by an extradural S1 root haemangioblastoma. Neuroradiology,2002, 44:494-8.
Kitahama K, Jouvet A, Fujimiya M, Nagatsu I, Arai R.5-Hydroxytryptophan (5-HTP) uptake and decarboxylation in the kitten brain.J Neural Transm, 2002, 109:683-9.
Lashford LS, Thiesse P, Jouvet A, Jaspan T, Couanet D, Griffiths PD, Doz F, Ironside J, Robson K, Hobson R, Dugan M, Pearson AD, Vassal G, Frappaz D; a United Kingdom Children's Cancer Study Group and French Society for PediatricOncology Intergroup Study. Temozolomide in malignant gliomas of childhood: a United Kingdom Children's Cancer Study Group and French Society for Pediatric Oncology Intergroup Study. J Clin Oncol, 2002, 20:4684-91.
Lutterbach J, Fauchon F, Schild SE, Chang SM, Pagenstecher A, Volk B, Ostertag C, Momm F, Jouvet A. Malignant pineal parenchymal tumors in adult patients: patterns of care and prognostic factors. Neurosurgery, 2002, 51:44-55.
Marec-Berard P, Jouvet A, Thiesse P, Kalifa C, Doz F, Frappaz D. Supratentorial embryonal tumors in children under 5 years of age: an SFOP study of treatment with postoperative chemotherapy alone.Med Pediatr Oncol, 2002,38:83-90.
Privat K, Brisson C, Jouvet A, Chesneau D, Ravault JP, Fevre-Montange M.Evidence for implication of tryptophan hydroxylase in the regulation of melatonin synthesis in ovine pinealocytes in culture. Cell Mol Neurobiol, 2002, 22:417-29.
Yapo Ette H, Koffi K, Botti K, Jouvet A, Effi AB, Honde M. Sudden death caused by parasites: postmortem cerebral malaria discoveries in the african endemic zone. Am J Forensic Med Pathol, 2002, 23:202-7.
2003
Baty V, Prost B, Jouvet A, Laurent J, Vallee B. Acute spinal cord compression and calcium pyrophosphate deposition disease. Case illustration. J Neurosurg, 2003, 99: 240.
Beauchesne PD, Pedeux RM, Bonmartin A, Bertrand S, Jouvet A, Kirchner AL, Revel R, Mornex F, Dore JF. Intracerebral C6 glioma model in female hairless rats: assessment by using MRI and follow-up of irradiation. Anticancer Res, 2003, 23:3755-6.
Champier J, Jouvet A, Rey C, Guyotat J, Fèvre-Montange M. Differential somatostatin receptor subtype expression in human normal pineal gland and pineal parenchymal tumors. Cell Mol Neurobiol, 2003, 23:101-13. Erratum in: Cell Mol Neurobiol, 2003, 23:875.
Jouvet A, Fauchon F, Liberski P, Saint-Pierre G, Didier-Bazes M, Heitzmann A, Delisle MB, Biassette HA, Vincent S, Mikol J, Streichenberger N, Ahboucha S, Brisson C, Belin MF, Fèvre-Montange M. Papillary tumor of the pineal region. Am J Surg Pathol, 2003, 27:505-12.
Peysson S, Nighoghossian N, Derex L, Jouvet A, Hermier M, Trouillas P.
Cerebral amyloid angiopathy revealed by transient ischemic events: contribution of MRI to diagnosis and pathophysiology studyRev Neurol (Paris),2003, 159:203-5.
Sunyach MP, Pommier P, Martel Lafay I, Guyotat J, Ginestet G, Jouanneau E, Jouvet A, Sindou M, Bret P, Carrie C, Frappaz D.Conformal irradiation for pure and mixed oligodendroglioma: the experience of Centre Leon Berard Lyon. Int J Radiat Oncol Biol Phys, 2003, 56:296-303.
Trouillas P, Honnorat J, Bret P, Jouvet A, Gerard JP.
Redifferentiation therapy in brain tumors: long-lasting complete regression of glioblastomas and an anaplastic astrocytoma under long term 1-alpha-hydroxycholecalciferol. J Neurooncol, 2001, 51:57-66.
2004
Giammarile F, Cinotti LE, Jouvet A, Ramackers JM, Saint Pierre G, Thiesse P, Jouanneau E, Guyotat J, Pelissou-Guyotat I, Setiey A, Honnorat J, Le Bars D, Frappaz D. High and low grade oligodendrogliomas (ODG): correlation of amino-acid and glucose uptakes using PET and histological classifications. J Neurooncol, 2004, 68:263-67.
Huang H, Okamoto Y, Yokoo H, Heppner FL, Vital A, Fèvre-Montange M, Jouvet A, Yonekawa Y, Lazaridis EN, Kleihues P, Ohgaki H. Gene expression profiling and subgroup identification of oligodendrogliomas. Oncogene, 2004, 23:6012-22.
Jouvet A*, Lellouch-Tubiana A*, Boddaert N, Zerah M, Champier J, Fevre-Montange M. Fourth ventricle neurocytoma with lipomatous and ependymal differentiation. Acta Neuropathol, 2005, 109:346-51. (* 2 premiers co-auteurs)
Peter L, Nighoghossian N, Jouvet A, Derex L, Hermier M, Philippeau F, Honnorat J, Trouillas P. Delayed post-anoxic leukoencephalopathy
Rev Neurol (Paris), 2004, 160 :1085-8.
2005
Lellouch-Tubiana A, Boddaert N, Bourgeois M, Fohlen M, Jouvet A, Delalande O, Seidenwurm D, Brunelle F, Sainte-Rose C. Angiocentric neuroepithelial tumor (ANET): a new epilepsy-related clinicopathological entity with distinctive MRI. Brain Pathol, 2005, 15:281-6.
Champier J, Jouvet A, Rey C, Brun V, Bernard A, Fevre-Montange M. Identification of differentially expressed genes in human pineal parenchymal tumors by microarray analysis. Acta Neuropathol,2005, 109:306-13.
Daumas-Duport C, Koziak M, Miquel C, Nataf F, Jouvet A, Varlet P. Reappraisal of the Sainte-Anne Hospital classification of oligodendrogliomas in view of retrospective studies. Neurochirurgie, 2005, 51:247-53.
Grill J, Sainte-Rose C, Jouvet A, Gentet JC, Lejars O, Frappaz D, Doz F, Rialland X, Pichon F, Bertozzi AI, Chastagner P,Couanet D, Habrand JL, Raquin MA, Le Deley MC, Kalifa C. Treatment of medulloblastoma with postoperative chemotherapy alone: an SFOP prospective trial in young children. Lancet Oncol, 2005, 6:573-80.
Lena G, Mottolese C, Paz-Paredes A, Scavarda D, Girard N, Gouvernet J, Jouvet A, Figarella-Branger D.Pediatric supratentorial oligodendrogliomas: Marseilles and Lyons experiences. Neurochirurgie, 2005, 51 : 400-9.
Nataf F, Koziak M, Ricci AC, Varlet P, Devaux B, Beuvon F, Roujeau T, Page P, Cioloca C, Turak B, Schlienger M, Touboul E, Haie-Meder C, Vannetzel JM, Dhermain F, Honnorat J, Jouvet A, De Saint-Pierre G, Daumas-Duport C, Bret P, Roux FX. Results of the Sainte-Anne - Lyons series of 318 oligodendroglioma in adults. Neurochirurgie, 2005, 51 : 329-51.
Rosenberg DS, Demarquay G, Jouvet A, Le Bars D, Streichenberger N, Sindou M, Kopp N, Mauguiere F, Ryvlin P. Methionine PET: dysembryoplastic neuroepithelial tumours compared with other epileptogenic brain neoplasms. J Neurol Neurosurg Psychiatry, 2005, 76 : 1686-92.
Varlet P, Jouvet A, Miquel C, Saint-Pierre G, Beuvon F, Daumas-Duport C. Criteria of diagnosis and grading of oligodendrogliomas or oligo-astrocytomas according to the WHO and Sainte-Anne classifications. Neurochirurgie, 2005, 51 : 239-46.
2006
Cotton F, Ongolo-Zogo P, Louis-Tisserand G, Streichenberger N, Hermier M, Jouvet A, Hlaihel C, Jouanneau E, Salles G, Froment JC. Diffusion and perfusion MR imaging in cerebral lymphomas.J Neuroradiol, 2006,33:220-8.
Fèvre-Montange M, Hasselblatt M, Figarella-Branger D, Chauveinc L, Champier J, Saint-Pierre G, Taillander L, Coulon A, Paulus W, Fauchon F*, Jouvet A*. Prognosis and histopathological features in papillary tumors of the pineal region : a retrospective multicenter study of 31 cases. J Neuropathol Exp. Neurol, 2006, 65 :1004-11 (*2 derniers co-auteurs).
Balenci L, Clarke ID, Dirks PB, Assard N, Ducray F, Jouvet A, Belin MF, Honnorat J, Baudier J. IQGAP1 protein specifies amplifying cancer cells in glioblastoma multiforme. Cancer Res, 2006, 66:9074-82.
Fèvre-Montange M, Champier J, Szathmari A, Wierinckx A, Mottolese C, Guyotat J, Figarella-Branger D, Jouvet A*, Lachuer J*. Microarray analysis reveals differential gene expression patterns in tumors of the pineal region. J Neuropathol Exp Neurol, 2006, 65:675-84 (*2 derniers co-auteurs)
Burel-Vandenbos F, Jouvet A, Chanalet S, Lonjon M, Cardot-Leccia N, Michiels JF. An unusual and misleading form of pilocytic astrocytoma. Ann Pathol, 2006,26:126-8.
Hasselblatt M, Blumcke I, Jeibmann A, Rickert CH, Jouvet A, van de Nes JA, Kuchelmeister K, Brunn A, Fèvre-Montange M, Paulus W. Immunohistochemical profile and chromosomal imbalances in papillary tumours of the pineal region. Neuropathol Appl Neurobiol, 2006, 32:278-83.
Jouanneau E, Guzman Tovar RA, Desuzinges C, Frappaz D, Louis-Tisserand G, Sunyach MP, Jouvet A, Sindou M. Very late frontal relapse of medulloblastoma mimicking a meningioma in an adult: usefulness of 1H magnetic resonance spectroscopy and diffusion-perfusion magnetic resonance imaging for preoperative diagnosis: case report. Neurosurgery, 2006, 58:E789.
Ghersi-Egea JF, Strazielle N, Murat A, Jouvet A, Buenerd A, Belin MF. Brain protection at the blood-cerebrospinal fluid interface involves a glutathione-dependent metabolic barrier mechanism. J Cereb Blood Flow Metab, 2006, 26:1165-75.
2007
Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, Scheithauer BW, Kleihues P. The 2007 WHO Classification of Tumours of the Central Nervous System. Acta Neuropathol, 2007, 114:97-109.
Sunyach MP, Jouvet A, Perol D, Jouanneau E, Guyotat J, Gignoux L, Carrie C, Frappaz D. Role of exclusive chemotherapy as first line treatment in oligodendroglioma. J Neurooncol, 2007, sous presse
Ponzoni M, Berger F, Chassagne-Clement C, Tinguely M, Jouvet A, Ferreri AJ, Dell'oro S, Terreni MR, Doglioni C, Weis J, Cerati M, Milani M, Iuzzolino P, Motta T, Carbone A, Pedrinis E, Sanchez J, Blay JY, Reni M, Conconi A, Bertoni F, Zucca E, Cavalli F, Borisch B; on Behalf of the International Extranodal Lymphoma Study Group (IELSG). Reactive perivascular T-cell infiltrate predicts survival in primary central nervous system B-cell lymphomas. Br J Haematol, 2007, 138:316-23.
Metellus P, Barrie M, Figarella-Branger D, Chinot O, Giorgi R, Jouvet A, Guyotat J. Intracranial ependymomas in adult patients. Retrospective analysis of 121 cases from the Multicentric French Study. Neurochirurgie, 2007, 5366-75.
Metellus P, Barrie M, Figarella-Branger D, Chinot O, Giorgi R, Gouvernet J, Jouvet A, Guyotat J. Multicentric French study on adult intracranial ependymomas: prognostic factors analysis and therapeutic considerations from a cohort of 152 patients. Brain, 2007,130:1338-49.
Figarella-Branger D, Metellus P, Barrie M, Maues de Paula A, Fernandez C, Polivka M, Vital A, Labrousse F, Vignaud JM, Laquerriere A, Rousselet MC, Lacroix C, Saikali S, Chapon F, Gontier MF, Chretien F, Babin P, Rigau V, Vandenbos F, Peoc'h M, Kujas M, Chinot O, Gouvernet J, Giorgi R, Guyotat J, Jouvet A. Intracranial ependymomas in adult patients. Diagnosis and histological prognostic factors. Neurochirurgie, 2007, 53:76-84.
Metellus P, Bouvier C, Guyotat J, Fuentes S, Jouvet A, Vasiljevic A, Giorgi R, Dufour H, Grisoli F, Figarella-Branger D. Solitary fibrous tumors of the central nervous system: clinicopathological and therapeutic considerations of 18 cases. Neurosurgery, 2007, 60:715-22.
Roch JA, Hermier M, Jouvet A, Nighoghossian N. Cerebral amyloid angiopathy. Rev Neurol (Paris), 2007, 163:134-7.
Revues
Jouvet A, Saint-Pierre G, Perrot X, Gerard A, Fevre-Montange M, Pialat J, Henin D. Practical recommendations for management of the biopsy in an expansive intra-cerebral process Ann Pathol, 2000, 20:507-12.
Mertens P, Guenot M, Hermier M, Jouvet A, Tournut P, Froment JL, Sindou M, Carret JP. Radiologic anatomy of the spinal dorsal horn at the cervical level (anatomic-MRI correlations). Surg Radiol Anat, 2000, 22:81-8.
Ouvrages
Fauchon F*, Jouvet A*, Alapetite C, Fèvre-Montange M. Classification des tumeurs de la région pinéale et leur traitement. EMC- Neurologie, 2005,17-370-A-10 : 1-16 (*deux premiers co-auteurs).
Jouvet A, Fauchon F, Bouffet E, Saint Pierre G, Champier J, Fèvre-Montange M. Tumors of pineal parenchymal and glial cells. In Russell and Rubinstein’s pathology of tumors of central nervous system. Seventh Edition. R.E. Mc Lendon, M.K. Rosenblum, D.D. Bigner. Chapter 33: 413-25. |
